As a corticosteroid, fluticasone propionate is a member of the drug family. It is used to treat permanent rhinitis as well as seasonal allergic rhinitis, which includes hay fever.
The pressure and pain in the sinuses brought on by allergic rhinitis are among the symptoms that can be controlled by it. The medication may not start to work fully for two to three days. It may take up to two weeks for some people to experience the full benefit.
A number of brands and/or dosage forms of this drug may be offered.
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- Fluticasone Propionate Nasal Spray.
- Flonase, the brand
- Fluticasone is used to treat allergic and non-allergic nasal symptoms that can occur at any time of year, including runny or stuffy noses, itching, and sneezing. Additionally, it can assist in easing itchy, watery eyes, which are common allergy eye symptoms. This medicine is part of the corticosteroid drug family.
7 Things You Should Know
1. How it works
Fluticasone nasal spray is also known as Flonase under commercial names.
By limiting the release of prostaglandins and other inflammatory mediators, Flonase (fluticasone) is supposed to act. Both inflammation and irritation are reduced with fluticasone. Furthermore, it can aid in blood vessel constriction.
As a corticosteroid, fluticasone is a member of the drug class. This particular corticosteroid is of the glucocorticoid class.
Flonase helps adults and children over the age of four who suffer from nasal symptoms such as a runny or stuffy nose, sneezing, and nasal itching.
Recommended for adults and children aged 4 and older to relieve the symptoms of permanent nonallergic rhinitis (constant nasal congestion and stuffiness).
Due to fluticasone’s high affinity for the glucocorticoid receptor, which is included in Flonase, there is a reduced risk of salt and water retention when using this medication (and therefore less likely to cause high blood pressure, low potassium levels, or high sodium levels).
Under the brand name fluticasone propionate nasal spray, a generic version of Flonase is offered.
The side effects that you are more likely to experience are listed below if you are between the ages of 18 and 60, do not take any other medications, or have any other medical conditions:
Nasal bleeding, nasal ulcers, nausea, coughing, headaches, sore throats, and burning or itching in the nose are further symptoms.
Flonase use can also delay wound healing and occasionally more severe nasal side effects. If you have just undergone nose surgery or nasal damage, avoid using Flonase.
Using nasal corticosteroids has been linked to glaucoma and cataracts. Spraying Flonase too close to the eyes should be avoided. Use exactly as instructed.
You can be more prone to viral illnesses like chickenpox, measles, and other infections if you use corticosteroids.
Flonase nasal spray use over a prolonged period of time may slow down a child’s growth.
Some individuals, such as those who have a weakened immune system, specific eye issues, certain allergies, an active infection, and other disorders, might not be able to use it.
Flonase may interact with various drugs that have a significant impact on hepatic enzymes, particularly CYP3A4, including antiviral drugs used to treat HIV (such as ritonavir and atazanavir), clarithromycin, itraconazole, ketoconazole, and nefazodone.
Studies on Flonase in expectant mothers are lacking in both quality and control. Rodents are more vulnerable to teratogenic effects than humans are, thus Flonase should only be used during pregnancy if the benefits outweigh the dangers.
Animal studies have shown that corticosteroids can cause birth defects at low concentrations. When a woman is pregnant, her body produces more corticosteroids naturally, so many of them may not be necessary.
Babies whose moms took corticosteroids throughout pregnancy have experienced hypoadrenalism. Although the presence of various corticosteroids in breast milk has been reported, it is unknown whether fluticasone propionate is excreted into it.
4. Bottom Line
Flonase lessens the swelling and rhinitis-related symptoms in the nose; nevertheless, Flonase can make you bleed from the nose, and it takes around three days to get the full results.
One or two dosages per day are permitted. Prior to usage, gently shake the Flonase.
If it has been more than a week since your last dose of Flonase, you will need to prime it before using it for the first time. By vigorously shaking the nasal spray and releasing six sprays into the air away from the face, this can be accomplished.
The typical Flonase dosage for adults is 2 sprays once daily or 1 spray twice daily into each nostril. After a few days, you may lower the dosage to 1 spray in each nostril, once per day. Flonase can be sprayed two times daily in each nostril for a maximum daily dose of two.
After using the medication for a few days, speak to your doctor if there is no improvement. The suggested dosage should not be exceeded.
Regular use is required for Flonase to work effectively.
When administered for allergic rhinitis symptoms, Flonase may take several days to take full action. Prior to Flonase starting to work, you might want to try a decongestant nasal spray (use for no more than three days) or an antihistamine.
Flonase shouldn’t be sprayed in your mouth or close to your eyes.
If you suffer a rash or allergic-like reaction while using Flonase, notice a change in your vision, or have any of these symptoms, consult your doctor.
Before using Flonase while breastfeeding or when pregnant, see your doctor.
6. Response and Effectiveness
Even though fluticasone, the active component of Flonase, is quickly absorbed via the nasal tissues, the symptoms of rhinitis are not immediately alleviated. To notice a noticeable reduction in symptoms, administration of Flonase may take several days.
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When combined with Flonase nasal spray, drugs that interact with it can either lessen its effects, shorten its duration, exacerbate adverse effects, or have no effect at all. There are situations when a drug interaction necessitates stopping the use of one of the drugs, but it is not always the case. The best way to handle drug interactions is to discuss it with your doctor.